Set in 1940s São Paulo, the story follows Laura, a modern woman devoted to the arts who is oppressed by her husband, Natércio Prado—a wealthy man with traditional views. Amidst marital turmoil, Laura suffers a severe trauma and is even committed to an asylum by her husband. The couple separates, and the family is torn apart: Laura keeps her youngest daughter, Virgínia, while Natércio retains custody of the other daughters, Otávia and Bruna. Frail and penniless, Laura moves into the Vila Mariana home of her neurologist, Daniel. He is in love with his patient and believes her condition is physical rather than mental. Laura hides the fact that Virgínia is actually Daniel's daughter. The youngest daughter eventually returns to live with her father, where she faces hostility and harshness from the housekeeper, Frau Herta.

Ciranda de Pedra ran for 1 season. No new episodes are scheduled.