Chiharu and her younger brother Junpei live together. Chiharu is 30-years-old and she is funny, but also has a sharp tongue. Junpei is a good brother and he is considerate to Chiharu. After they come home from work, they eat and drink together. Doing that, they talk about various subjects like love, work, and their interests.

Boku no Nee-chan ran for 1 season. No new episodes are scheduled.