Mary Rose Byrne (born 24 July 1979) is an Australian actress. She made her screen debut in the film Dallas Doll (1994), and continued to act in Australian film and television throughout the 1990s. She obtained her first leading film role in The Goddess of 1967 (2000), which brought her the Volpi Cup for Best Actress and made the transition to Hollywood in the small role of Dormé in Star Wars: Episode II – Attack of the Clones (2002), followed by larger parts in Troy (2004), 28 Weeks Later (2007), and Knowing (2009). Byrne appeared as Ellen Parsons in the legal thriller series Damages (2007–2012), which earned her two Golden Globe Awards nominations and two Primetime Emmy Award nominations. Get Him to the Greek (2010) and Bridesmaids (2011) established her as a comedic actress, in addition to the dramas and thrillers in which she continues to appear. She has since starred in a number of commercially successful comedies and dramas, including Insidious (2010) and its sequel Insidious: Chapter 2 (2013), X-Men: First Class (2011) and its sequel X-Men: Apocalypse (2016), Annie (2014), as well as Peter Rabbit (2018) and its sequel Peter Rabbit 2: The Runaway (2021). Byrne also portrayed Gloria Steinem in the miniseries Mrs. America (2020) and led the comedy series Physical (2021–2023) and Platonic (2023). Byrne has been in relationship with American actor Bobby Cannavale since 2012 and they have two sons. And she is the sister-in-law of New Zealand actress Rose McIver from her brother's marriage.

Filmography

• 2026Fallen Angels — Jane Banbury
• The Good Daughter — Samantha Quinn, Executive Producer
• 2026Tow — Amanda Ogle, Producer
• 2025If I Had Legs I'd Kick You — Linda, Executive Producer
• 2024Ezra — Jenna
• 2023Insidious: The Red Door — Renai Lambert
• Platonic — Sylvia, Executive Producer
• 2023Teenage Mutant Ninja Turtles: Mutant Mayhem — Leatherhead (voice)
• 2023Tree's Blood — Zamora (voice)
• 2022G'day — Ruby (voice)
• 2022Seriously Red — Elvis, Executive Producer
• 2022Spirited — Ms. Blansky
• 2021Peter Rabbit 2: The Runaway — Bea
• Physical — Sheila Rubin, Executive Producer
• 2021Puff: Wonders of the Reef — Narrator (voice)
• 2021Shark — Sofie
• 2020Irresistible — Faith Brewster
• 2020Like a Boss — Mel Paige
• Mrs. America — Gloria Steinem
• 2019I Am Mother — Mother (voice)
• 2019Jexi — Jexi (voice)
• The Boys — Rose Byrne (uncredited)
• Bluey — Brandy (voice)
• 2018Insidious: The Last Key — Renai Lambert (archival footage)
• 2018Instant Family — Ellie Wagner
• 2018Juliet, Naked — Annie Platt
• 2018Peter Rabbit — Beatrix 'Bea' Potter / Jemima Puddle-Duck (voice)
• 2017I Love You, Daddy — Grace Cullen
• 2017Martha the Monster — Martha
• 2017The Immortal Life of Henrietta Lacks — Rebecca Skloot
• Angie Tribeca — Norrah Newt
• 2016Neighbors 2: Sorority Rising — Kelly Radner
• 2016The Meddler — Lori Minervini
• 2016X-Men: Apocalypse — Moira MacTaggert
• 2015Spy — Raina Boyanov
• 2015Unity — Narrator (voice)
• 2014Adult Beginners — Justine
• 2014Annie — Grace Farrell
• Last Week Tonight with John Oliver — Boeing Executive
• 2014Neighbors — Kelly Radner
• 2014This Is Where I Leave You — Penny Moore
• 2013I Give It a Year — Nat
• 2013Insidious: Chapter 2 — Renai Lambert
• 2013The Internship — Dana Simms
• 2013The Place Beyond the Pines — Jennifer Cross
• 2013The Turning — Rae
• 2011Bridesmaids — Helen
• 2011Insidious — Renai Lambert
• Portlandia — Fred's Girlfriend
• 2011X-Men: First Class — Moira MacTaggert
• 2010Get Him to the Greek — Jackie Q
• 2010I Love You Too — Verity
• 2009Adam — Beth Buchwald
• 2009Knowing — Diana Wayland
• 2008The Tender Hook — Iris
• 200728 Weeks Later — Scarlet
• Damages — Ellen Parsons
• 2007Just Buried — Roberta Knickle
• 2007Sunshine — Cassie
• 2006Marie Antoinette — Duchesse de Polignac
• 2006The Dead Girl — Leah
• 2006The Tenants — Irene Bell
• American Dad! — Jenny (voice)
• Casanova — Edith
• 2004Troy — Briseis
• 2004Wicker Park — Alex
• 2003I Capture the Castle — Rose Mortmain
• 2003Take Away — Sonja Stilano
• 2003The Night We Called It a Day — Audrey Appleby
• 2003The Rage in Placid Lake — Gemma Taylor
• 2002City of Ghosts — Sabrina
• 2002Star Wars: Episode II - Attack of the Clones — Dormé
• 2001The Pitch — Girl
• 2000My Mother Frank — Jenny
• 2000The Goddess of 1967 — B.G.
• 1999The Date — Sophie
• 1999Two Hands — Alex
• Big Sky — Angie
• Murder Call
• Echo Point — Belinda O'Connor
• 1994Dallas Doll — Rastus Sommers
• Late Night with Conan O'Brien
• Screen Two — Rastus
• Nasty

Appearances as themselves (25)

• 2025Legacy of Screams: The Evolution of Horror Movies — Self (archive footage)
• The Kelly Clarkson Show — Self
• Close Up with The Hollywood Reporter — Self
• Hot Ones — Self
• The Late Show with Stephen Colbert — Self - Guest
• Late Night with Seth Meyers — Self - Guest
• Off Camera with Sam Jones — Self
• The Tonight Show Starring Jimmy Fallon — Self, Self - Guest
• Hollywood Game Night — Self
• 2011Children of the Atom - Filming X-Men: First Class — Self
• 2010Gaze — Self (archive footage)
• 2009Knowing All: The Making of a Futuristic Thriller — self
• 2009Knowing: Visions of the Apocalypse — self (archival footage)
• Late Night with Jimmy Fallon — Self - Guest
• The Justin Lee Collins Show — Self - Guest
• Watch What Happens Live with Andy Cohen — Self - Guest
• 2007Code Red: The Making of '28 Weeks Later' — Self
• Project Runway — Self - Guest Judge
• Jimmy Kimmel Live! — Self - Guest
• Rove — Self
• The View — Self
• LIVE with Kelly and Mark — Self - Guest
• Jeopardy! — Self - Clue Presenter
• The Oscars — Self
• Golden Globe Awards — Self - Nominee