Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble (2022) have earned her nominations at the Primetime Emmy Awards. Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025). Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023). Description above from the Wikipedia article Lizzy Caplan, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Filmography

• 2027Drag — Executive Producer
• 2025Now You See Me: Now You Don't — Lula
• Zero Day — Alexandra Mullen
• 2023Cobweb — Carol
• Fatal Attraction — Alex Forrest
• Fleishman Is in Trouble — Libby Epstein
• 2022The People We Hate at the Wedding — Marissa
• Inside Job — Reagan Ridley (voice)
• 2019The Toll Road — Emily
• Truth Be Told — Lanie Buhrman / Josie Buhrman
• Castle Rock — Annie Wilkes
• Das Boot — Carla Monroe
• 2018Extinction — Alice
• Ill Behaviour — Nadia
• 2017The Disaster Artist — Lizzy Caplan
• 2016Allied — Bridget Vatan
• Angie Tribeca — Deirdre
• 2016Now You See Me 2 — Lula
• 2015The Night Before — Diana
• 2014Beef — Audrey
• 2014The Interview — Agent Lacey
• Masters of Sex — Virginia Johnson
• 2013The Sidekick — Bailey
• 20123, 2, 1... Frankie Go Boom — Lassie
• 2012Bachelorette — Gena Myers
• 2012High Road — Sheila
• 2012Marvel One-Shot: Item 47 — Claire Wise
• 2012Queens of Country — Jolene Gillis
• 2012Save the Date — Sarah
• 2011Home for Actresses — Lizzy
• Mr. Sunshine — Vivian Cornelli
• New Girl — Julia Cleary
• 2010127 Hours — Sonja Ralston
• 2010Hot Tub Time Machine — April
• 2010Successful Alcoholics — Lindsay, Producer
• 2010The Last Rites of Ransom Pride — Juliette Flowers
• 2009Crossing Over — Marla
• Party Down — Casey Klein
• The Cleveland Show
• The League — Rebecca Ruxin
• Childrens Hospital — Casey Klein, Harmony
• 2008Cloverfield — Marlena
• 2008My Best Friend's Girl — Ami
• True Blood — Amy
• 2007Crashing — Jacqueline
• 2006Love Is the Drug — Sara Weller
• The Class — Kat Warbler
• American Dad! — Debbie (voice)
• Related — Marjee Sorelli
• 2004Mean Girls — Janis Ian
• 2003Hardcore Action News — Lizzy Lyons
• The Pitts — Faith Pitt
• Tru Calling — Avery Bishop
• 2002Everybody's Doing It — Angela
• 2002Orange County — Party Girl
• Smallville — Tina Greer
• Undeclared — Beautiful Girl
• 2000From Where I Sit — Lily
• Family Guy — Woman Arguing With Quagmire (voice)
• Freaks and Geeks — Sara
• Once and Again
• The Simpsons — Virginia Johnson (voice)
• Darkwing Duck — Gosalyn Mallard (voice)
• Far Cry
• The Boys from Brazil — Hannah Liebermann

Appearances as themselves (12)

• 20197 Up & Me — Self
• Chelsea — Self
• Close Up with The Hollywood Reporter — Self
• Late Night with Seth Meyers — Self - Guest
• Off Camera with Sam Jones — Self
• The Tonight Show Starring Jimmy Fallon — Self
• The Last Leg — Self
• Comedy Bang! Bang! — Self
• Conan — Self
• Watch What Happens Live with Andy Cohen — Self - Guest
• Jimmy Kimmel Live! — Self, Self - Guest
• The View — Self