Yuuta Takemoto, Takumi Mayama, and Shinobu Morita are college students who share the small apartment. Even though they live in poverty, the three of them are able to obtain pleasure through small things in life. The story follows these characters' life stories as poor college students, as well as their love lives when a short but talented 18 year old girl called Hagumi Hanamoto appears.

Honey and Clover ran for 2 seasons. No new episodes are scheduled.