The story revolves around Shu Ouma, a high school boy who inadvertently obtains an ability called "The Power of the Kings" that enables him to draw out items called "Voids" from other people. He is then thrown into the conflict between a resistance group called Funeral Parlor which aims to restore Japan's independence from a quasi-governmental organization known as the GHQ. In the process, Shu has to deal with the burden his ability puts on his shoulders and the horrific mystery of his past.

Guilty Crown ran for 1 season. No new episodes are scheduled.