Itsuki Hashima is a light novelist obsessed with little sisters, strictly focusing on them when he writes his stories. Despite his personality, he's surrounded by a tight circle of friends, including a beautiful genius writer who loves him, a big-sisterly college classmate, a fellow male writer, a sadistic tax accountant, his editor, and Chihiro, his perfect younger step-brother who takes care of the housework and cooking. As the story progresses, the underlying conflicts of dreams and goals surface, as each character attempts to achieve their dreams, in their own way.

A Sister's All You Need ran for 1 season. No new episodes are scheduled.